How long does vecuronium last

It blocks transmission of motor nerve impulses to the striated muscle receptors causing muscle relaxation and paralysis. The onset of action for Vecuronium is 2 — 5 minutes.

The duration of action varies with dose and age but is approximately 60 minutes in infants. Vecuronium is less likely to cause cardiovascular effects and does not release clinically significant amounts of histamine so may be preferable to Pancuronium. It is used for unstable babies in whom it is desirable that they are not breathing against the ventilator.

The desirable effects of Vecuronium are improvement of ventilation and oxygenation and minimisation of fluctuations in cerebral blood flow. Note : Dosage may need reduction if used with other anaesthetic or neuromuscular blocking drugs. CAUTION in patients with encephalopathy — muscle relaxation may make neurological assessment difficult and mask seizures.

Remain by the bedside until effects of IV bolus Vecuronium are complete or the IV infusion has been running for at least 30 minutes. Uncommon drugs have simply been omitted and may be incompatible. For this reason please avoid mixing the two together or administering via Y-site. Whilst great care has been taken to check the information is accurate, it is possible that errors may have been missed.

Furthermore, dosage schedules are continually being revised and new side effects recognised. For these reasons, the reader is strongly advised to consult the drug companies' printed information before administering any of the drugs recommended in this book.

Most drugs in this document are appropriate only for specialist use in hospitals. A number of drugs should only be used in consultation with the appropriate Paediatric subspecialist.

Note: The electronic version of this guideline is the version currently in use. Any printed version cannot be assumed to be current. Printed copies of this document are valid for. The Royal Children's Hospital Melbourne. Vecuronium Description and indication for use Vecuronium is a non-depolarising muscle relaxant shorter-acting than Pancuronium. Higher infusion rates may be required and duration of action may be shortened in patients receiving long-term carbamazepine or phenytoin.

IV Infants 7 wk— 1 yr : 0. Toxicity Overdose: If overdose occurs, use peripheral nerve stimulator to determine the degree of neuromuscular blockade. Maintain airway patency and ventilation until recovery of normal respirations occurs. To view other topics, please log in or purchase a subscription. Handbook covers dosage, side effects, interactions, uses. Complete Product Information. We're glad you have enjoyed Davis's Drug Guide! As a thank-you for using our site, here's a discounted rate for renewal or upgrade.

Not now - I'd like more time to decide. Renew my subscription. Davis's Drug Guide. Tags Type your tag names separated by a space and hit enter. Citation Vallerand, April Hazard. Davis Company, Davis Company; Accessed November 12, Vallerand, A. In Davis's Drug Guide 16th edition. Davis Company. Vecuronium [Internet]. In: Davis's Drug Guide. Your free 1 year of online access expired.