What is citrulline antibody test

Was This Helpful? Share Facebook Twitter Email. What Patients Need to Know. Rheumatoid Arthritis Diet Patient Stories. Subscribe to CreakyJoints for more related content. About CreakyJoints CreakyJoints is a digital community for millions of arthritis patients and caregivers worldwide who seek education, support, advocacy, and patient-centered research. Our Resources ghlf. Stay Connected. The contents of this website are for informational purposes only and do not constitute medical advice.

Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. All rights reserved. Part of the Global Healthy Living Foundation, a c 3 non-profit organization. Reservados todos los derechos. It's often done along with or after a rheumatoid factor RF test. Rheumatoid factors are another type of autoantibody. RF tests used to be the main test to help diagnose rheumatoid arthritis. But RF factors can be found in people with other autoimmune diseases and even in some healthy people.

Many studies have shown that CCP antibodies provide a more accurate diagnosis of rheumatoid arthritis compared with RF testing. You may also need this test if other tests couldn't confirm or rule out a diagnosis of rheumatoid arthritis. A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial.

You may feel a little sting when the needle goes in or out. This usually takes less than five minutes. Be sure to tell your health care provider about all medicines, vitamins, and dietary supplements you are taking. You may need to stop taking certain substances for 8 hours before your test. There is very little risk to having a blood test.

You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly. If your CCP antibody results were positive, it means these antibodies were found in your blood. A negative result means no CCP antibodies were found. The meaning of these results may depend on the results of a rheumatoid factor RF test as well as a physical exam. Learn more about laboratory tests, reference ranges, and understanding results.

Rheumatoid arthritis can be difficult to diagnose, especially in its early stages. These include x-rays of your joints and the following blood tests:. These blood tests can show signs of inflammation. Diagnostic and clinical value of anti-cyclic citrullinated peptide antibodies compared with rheumatoid factor isotypes in rheumatoid arthritis.

Annals of the Rheumatic Diseases ; Castelar Pinheiro, G. Rauscher, M. Antibodies may help predict rheumatoid arthritis. Douglas, D. Antibodies Predict Course of Early Arthritis. Schellekens, G. Volume , Number 1, January , [On-line journal]. Pp Wu, A. Saunders Elsevier, St. Louis, Missouri. Kelly, J.

Medscape Medical News [On-line information]. Accessed on Medscape from Arthritis Res Ther. Smith, H. Rheumatoid Arthritis. Emery, P. Medscape from Rheumatology. Fox, D. Fox, MD. Medscape Rheumatology [On-line information]. Niemeier, L. CAP Newspath [On-line information]. American College of Rheumatology [On-line information]. Makover, M. Updated February Rheumatoid arthritis. MedlinePlus Medical Encyclopedia [On-line information].

Accessed January Updated August. Temprano, K. Updated December Medscape Reference [On-line information]. Updated September. Questions and Answers about Arthritis and Rheumatic Diseases. Aletaha, D. Pagana, K. McPherson R, Pincus M, eds. August 1, Center for Disease Control and Prevention. Accessed February Updated December American College of Rheumatology. Rheumatoid Arthritis, Who gets rheumatoid arthritis?

Accessed March October Kavanaugh, A.